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pentobarbital will lower the level or outcome of efavirenz by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.pentobarbital will lower the level or effect of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.pentobarbital will lower the extent or outcome of doravirine by